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Dr. Brett Tyler is the Director of OSU’s Center for Genome Research and Biocomputing (CGRB). He has also been appointed as the Stewart Chair in Gene Research, tenured Professor in the Department of Botany & Plant Pathology, and adjunct faculty in the College of Veterinary Medicine. Dr. Tyler has been a Professor at the Virginia Bioinformatics Institute and at the Department of Plant Pathology, Physiology and Weed Science at Virginia Polytechnic Institute and State University. Prior to joining VBI in 2002, he was a faculty member in the Department of Plant Pathology at the University of California, Davis for 14 years. In addition, Dr. Tyler has been a Damon Runyon-Walter Winchell Cancer Fund fellow, Willie Commelin Scholten Foundation Visiting Chair of Phytopathology in the Netherlands, a Fulbright Lecturer, a National Science Foundation Distinguished Lecturer, and a recipient of the American Phytopathological Society's Noel T. Keen Award for Research Excellence in Molecular Plant Pathology.
His research interests include the comparative and functional genomics of oomycete plant pathogens, the molecular analysis of oomycete virulence (effector) proteins, the functional genomics of quantitative disease resistance and infection responses in plants, computational prediction of gene functions, and mathematical modeling of complex cellular responses. A team led by him recently published the identification of phosphatidylinositol-3-phosphate as the cell entry receptor for oomycete and fungal effector proteins, in the journal Cell.
Professor & Director of Center for Genome Research and Biocomputing, Oregon State University